Advanced imaging
Light-sheet microscopy captures parallel EVs and 3D cell structures, while structured illumination preserves nanoscale detail across heterogeneous samples.

Unlocking precision medicine through extracellular vesicles.
✶Our Vision?
Becoming the golden standard for EV characterization in research and clinical applications.
☌How We Do It?
Through next-generation imaging flow cytometry delivering unprecedented EV analysis.
Accuracy
Single Vesicle Fidelity
Structured Illumination and Lightsheet microscopy for reliable single vesicle analysis,phenotyping and biomarker colocalization.
Scalability
Optofluidic Integration in Single Glass Chip
Femtosecond laser fabricated optofluidic components in a single glass chip enable alignment-free, compact, and scalable design.
Automation
Throughput and End-to-end Orchestration
Automated microfluidic control for high-throughput data acquisition and AI-powered real-time analysis.
Mission
Lumnora delivers a compact imaging flow cytometer that listens to the extracellular vesicle traffic of every cell. In one automated run, labs gain the sharpness of super-resolution microscopy, the sensitivity of light-sheet microscopy, the throughput of cytometry, and AI-ready datasets that translate straight into clinical programs.
Biology decoded
Single vesicles become rich biomarker sources, not noisy background.
Insight on demand
Automated analytics turn imaging runs into decision-ready dashboards.
All-in-one instrument
First platform to combine spatial and molecular information for end-to-end EV characterization.

Technology
Photonics, microfluidics, and AI collapse into one workflow so teams move from raw biofluids to vesicle signatures in a single session.
Advanced imaging
Light-sheet microscopy captures parallel EVs and 3D cell structures, while structured illumination preserves nanoscale detail across heterogeneous samples.
Microfluidic orchestration
Automated sample handling keeps vesicle streams aligned without manual intervention.
AI decision engine
Edge AI delivers instant annotations and orchestrates downstream decisions.
>2x resolution >95% detection
>50k EVs/min >5x throughput
~90% faster analysis
Research proof points
Strategic partnerships convert optical breakthroughs into validation data and regulatory-ready workflows.
Validated proof-of-concept
Four papers on technology and multi-cell applications, backed by two key patents.
Partner-driven roadmap
Prototype adaptation for EV analysis in a user-oriented development. Early collaborations provide fast feedback to finalize a platform for real clinical needs.
Regulatory runway
Long-term roadmap toward clinical adaptation, building the evidence and compliance needed for medical device certification.
Team

Giulio Coccia
CEO
Driving force behind Lumnora: uncovered the market opportunity, assembled the team, and built a strong early network in the EV field.

Niccolò Rondelli
CTO
Bridging biology and AI: leads tech development with a background in EVs, biomedical engineering, and AI.

Federico Nobili
CFO
Actively involved in entrepreneurial and investment projects alongside his financial background.

Andrea Bassi
Microscopy
Politecnico di Milano professor steering optical architecture and integration.

Francesca Bragheri
Photonics
CNR researcher advancing the optofluidic chip and photonic miniaturisation.

Petra Paiè
Microfluidics
Politecnico associate professor leading microfluidic automation and reliability.
Contact
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